Chestnut leaf extracts and antibiotic resistance

An interesting publication about the sensitivity of Staphylococcus aureus to European Chestnut (Castanea sativa) leaf extracts. These extracts were traditionally used in folk medicine to treat skin and soft tissue infections. The active compounds within the chestnut extracts showed that quorum sensing (a way for bacteria to communicate with each other; the phenomenon is related to bacterial colonization and virulence) by the bacteria could be inhibited. The authors indicate that this finding may be interesting since S. aureus has shown antibiotic resistance (e.g. the strain Methicillin-Resistan S. aureus)..

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0136486